ABSTRACT
Background: The prevalence of depression and anxiety in diabetes is considerably higher than normal population and found to have a negative impact on diabetes. Objective: The present study aimed at assessing the prevalence of anxiety and depression among outpatients receiving treatment for diabetes. Materials and Methods: Ours was a cross-sectional study where data was collected from 100 consecutive patients receiving treatment from the outpatient department of a teaching hospital for diabetes mellitus. The socio-demographic details were collected with the help of a self-structured questionnaire. Hamilton Rating Scale for Depression (H.D.R.S.) and Amritsar Depressive Inventory (A.D.I.) and Hamilton Anxiety Rating Scale (H.A.R.S.) were used to assess the presence and severity of depression and anxiety. The details regarding the diabetes included the duration of the condition, family history of diabetes, if any, and Body Mass Index (BMI). Results: The study sample consisted of 34 male and 66 female patients and their average age was 54.2 years. Most of the patients had mild depression, as indicated by an A.D.I. score of 8 to 13. Significant anxiety symptoms were seen in 30% of the patients. Most of the patients were having mild to moderate anxiety. Depression and anxiety was more prevalent in Type 2 diabetic patients in comparison to Type 1 diabetic patients. Conclusion: The comorbidity of depression, anxiety and diabetes mellitus is frequent. Depression and anxiety are more commonly associated with Type-2 Diabetes Mellitus. These findings underscore the need to screen all diabetic patients for the presence of psychiatric disorders.
ABSTRACT
Background: The prevalence of depression and anxiety in diabetes is considerably higher than normal population and found to have a negative impact on diabetes. Objective: The present study aimed at assessing the prevalence of anxiety and depression among outpatients receiving treatment for diabetes. Materials and Methods: Ours was a cross-sectional study where data was collected from 100 consecutive patients receiving treatment from the outpatient department of a teaching hospital for diabetes mellitus. The socio-demographic details were collected with the help of a self-structured questionnaire. Hamilton Rating Scale for Depression (H.D.R.S.) and Amritsar Depressive Inventory (A.D.I.) and Hamilton Anxiety Rating Scale (H.A.R.S.) were used to assess the presence and severity of depression and anxiety. The details regarding the diabetes included the duration of the condition, family history of diabetes, if any, and Body Mass Index (BMI). Results: The study sample consisted of 34 male and 66 female patients and their average age was 54.2 years. Most of the patients had mild depression, as indicated by an A.D.I. score of 8 to 13. Significant anxiety symptoms were seen in 30% of the patients. Most of the patients were having mild to moderate anxiety. Depression and anxiety was more prevalent in Type 2 diabetic patients in comparison to Type 1 diabetic patients. Conclusion: The comorbidity of depression, anxiety and diabetes mellitus is frequent. Depression and anxiety are more commonly associated with Type-2 Diabetes Mellitus. These findings underscore the need to screen all diabetic patients for the presence of psychiatric disorders.
ABSTRACT
Ebola Virus Disease or Ebola Haemorrhagic Fever is one of the highly fatal viral disease caused by ebola virus in humans. Mortality rate as high as 90% is reported. Virus is transmitted to humans through bats and other animals infected from bats. Although Ebola Virus Disease is reported since 1976 but currently West Africa is facing the largest outbreak of disease with danger of spread to other parts of the world. More than 5000 cases with mortality of more than 2600 cases has been reported till the end of 3rd quarter of year 2014. There is no specific treatment and vaccination available till date. Mainstay for managing patient is supportive care with early fluid resuscitation and symptomatic treatment. Our main target is to prevent human transmission by educating and supporting the community.
ABSTRACT
Ventilator-associated pneumonia (VAP) is a type of hospital acquired pneumonia commonly encountered in patients who receive mechanical ventilation and is associated with significant mortality and morbidity. VAP is associated with prolonged ventilation, increased antibiotic use, emergence of multidrug resistant organisms, prolonged critical care unit stay resulting in increased cost of care. It has been reported to occur in 9 to27 percent of all intubated patients. As per International Nosocomial Infection Control Consortium (INICC) report data summary, the overall rate of VAP was 13.6 per 1,000 ventilator days. Preventive measures, early diagnosis and treatment of VAP result in better outcome. The aim of this review was to search the literature for incidence, various risk factors, etiology, pathogenesis, treatment, and prevention of VAP. A literature search for VAP was done through the PUBMED/MEDLINE database. VAP is a commonly encountered nosocomial infection occurring in ventilated patients and is associated with increased mortality and morbidity. Outcome of patient with VAP depends on hospital setting, patient group, infection control policy, early diagnosis and judicious antibiotic use.
ABSTRACT
An originally isolated baculovirus, Spodoptera litura multiple nucleopolyhedrovirus (SpltMNPV) was serially passed through the S. litura larvae for upto four generations to determine the mean number of occlusion bodies (OBs) harvested per larva and their efficacy in terms of infectivity, feeding cessation and speed of kill of host larvae. The results revealed that the mean number of OBs harvested per larva increased significantly with increase in the dose of SpltMNPV at each passage and the yield was significantly lower in original stock wild-type SpltMNPV (P0) as compared to serially passed SpltMNPV (P1, P2, P3 and P4). Laboratory bioassays indicate that median lethal doses (LD50), median times to feeding cessation (FT50) and median survival times (ST50) of P0, P1, P2, P3 and P4 were significantly different from each other. The OBs of each passage when tested for their cross-infectivity against Spodoptera exigua and Spilarctia obliqua revealed significant reduction in their mortality. These results indicate that serially passed SpltMNPV is more host specific and more effective biocontrol agent than the original stock wild-type virus and can be adopted for mass production as a viral pesticide for control of the S. litura.